Publications
Karbakayghareh A, Pelzer B, Chin CR, Melnick AM, Barisic D, Leslie CS
Deep dynamical models of single-cell multiomic velocities predict loss-of-function and rescue perturbations in B cells.
bioRxiv · 2026 ·
DOI ·
PubMed
Pelzer B, Meydan C, Spiegel IM, Karagiannidis I, Xia M, Teater M, Welter EM, Searcy ZE, Hilton LK, Barisic D, Fong A, Fa P, Sethi S, Isgor IS, Fielding JJ, Karbalayghareh A, Burdette CS, Tumuluru S, Debek SM, Lee S, Massoni-Badosa R, Durmaz C, Salataj E, Pararajalingam P, Chen Z, Pelzl RJ, Shah S, Rivas MA, Hoehn KB, Mlynarczyk C, Isles HM, Wang X, Dogan A, Elenitoba-Johnson KSJ, Scott DW, Dreval K, Morin RD, Leslie CS, Puri R, Geri JB, Chin CR, Chadburn A, Mason CE, Reinhardt HC, Anguera MC, Béguelin W, Venturutti L, Melnick AM
SPEN loss drives extra-follicular diffuse large B cell lymphoma with female-specific lethality and therapeutic vulnerabilities.
Cancer Discovery · 2026 ·
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PubMed
Kriege O, Böll B, Brüder N, Lanznaster J, Mertins S, Minti A, Naendrup JH, Schmidt-Hieber M, Seggewiss-Bernhardt R, Weber P, Wille K, Panse J, Hentrich M, Schalk E; SECRECY Investigators.
Shortening of central venous catheter time in men with hematological and oncological diseases for prevention of central venous catheter-related bloodstream infections: a target-trial-emulation study.
Infection · 2026 ·
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PubMed
Schmidt-Hieber M, Kriege O, Panse J, Naendrup JH, Böll B, Hentrich M, Teschner D, Schalk E; SECRECY Investigators.
Incidence of central venous catheter-related bloodstream infections before, during, and after the SARS-CoV-2 pandemic: a registry-based cohort study.
Antimicrob Resist Infect Control. · 2025 ·
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PubMed
Buyukkaplan D, Canpolat Y, Cuschieri A, Inan D, Koc D, Pelzer B.
Inclusion of medical students in the next generation of clinician scientist training programs
Nature Medicine · 2025 ·
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PubMed
Tumuluru S, Godfrey JK, Cooper A, Yu J, Chen X, MacNabb BW, Venkataraman G, Zha Y,Pelzer B, Song J, Duns G, Sworder BJ, Raj S, Bolen C, Penuel E, Postovalova E, Kotlov N, Bagaev A, Fowler N, Shouval R, Smith SM, Alizadeh AA, Steidl C, Kline J.
Integrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody response
Blood · 2025 ·
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PubMed
Barisic D, Chin CR, Meydan C, Teater M, Tsialta I, Mlynarczyk C, Chadburn A, Wang X, Sarkozy M, Xia M, Carson SE, Raggiri S, Debek S, Pelzer B, Durmaz C, Deng Q, Lakra P, Rivas M, Steidl C, Scott DW, Weng AP, Mason CE, Green MR, Melnick AM.
ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
Cancer Cell · 2024 ·
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PubMed
Flümann R, Hansen J, Meinel J, Pfeiffer P, Goldfarb Wittkopf H, Lütz A, Wirtz J, Möllmann M, Zhou T, Tabatabai A, Lohmann T, Jauch M, Beleggia F, Pelzer B, Ullrich F, Höfmann S, Arora A, Persigehl T, Büttner R, von Tresckow B, Klein S, Jachimowicz RD, Reinhardt HC, Knittel G
An inducible Cd79b mutation confers ibrutinib sensitivity in mouse models of Myd88-driven diffuse large B-cell lymphoma
Blood Adv · 2024 ·
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PubMed
Mlynarczyk C, Teater M, Pae J, Chin CR, Wang L, Arulraj T, Barisic D, Papin A, Hoehn KB, Kots E, Ersching J, Bandyopadhyay A, Barin E, Poh HX, Evans CM, Chadburn A, Chen Z, Shen H, Isles HM, Pelzer B, Tsialta I, Doane AS, Geng H, Rehman MH, Melnick J, Morgan W, Nguyen DTT, Elemento O, Kharas MG, Jaffrey SR, Scott DW, Khelashvili G, Meyer-Hermann M, Victora GD, Melnick AM.
BTG1 mutation yields supercompetitive B cells primed for malignant transformation
Science · 2023 ·
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PubMed
Flümann R, Hansen J, Pelzer B, Nieper P, Lohmann T, Kisis I, Riet T, Kohlhas V, Nguyen PH, Peifer M, Abedpour N, Bosco G, Thomas RK, Kochanek M, Knüfer J, Jonigkeit L, Beleggia F, Holzem A, Büttner R, Lohneis P, Meinel J, Ortmann M, Persigehl T, Hallek M, Calado DP, Chmielewski M, Klein S, Göthert JR, Chapuy B, Zevnik B, Wunderlich FT, von Tresckow B, Jachimowicz RD, Melnick AM, Reinhardt HC, Knittel G.
Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
Blood Cancer Discovery · 2023 ·
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PubMed
Venturutti L, Rivas MA, Pelzer B, Flümann R, Hansen J, Karagiannidis I, Xia M, McNally DR, Isshiki Y, Lytle A, Teater M, Chin CR, Meydan C, Knittel G, Ricker E, Mason CE, Ye X, Pan-Hammarström Q, Steidl C, Scott DW, Reinhardt HC, Pernis AB, Béguelin W, Melnick AM.
An Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas
Cancer Discovery · 2023 ·
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PubMed
Aktar I, Cavdaroglu S, Goeschl S, Pelzer B, Rostkowska O, Stevanovski G.
Mentoring for future physician scientists
Nature Immunology · 2021 ·
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PubMed
Cramer P, Tausch E, von Tresckow J, Giza A, Robrecht S, Schneider C, Fürstenau M, Langerbeins P, Al-Sawaf O, Pelzer B, Fink AM, Fischer K, Wendtner CM, Eichhorst B, Kneba M, Stilgenbauer S, Hallek M.
Durable remissions following combined targeted therapy in patients with CLL harboring TP53 deletions and/or mutations
Blood · 2021 ·
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PubMed
Rostkowska OM, Peters A, Montvidas J, Magdas TM, Rensen L, Zgliczyński WS, Durlik M, Pelzer B
Attitudes and Knowledge of European Medical Students and Early Graduates about Vaccination and Self-Reported Vaccination Coverage-Multinational Cross-Sectional Survey
Int J Environ Res Public Health · 2021 ·
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PubMed
Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer B, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G.
An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities
Blood Cancer Discovery · 2021 ·
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PubMed
Kabanova A, Gavriilaki E, Pelzer B, Brunetti L, Maiques-Diaz A
Effect of the COVID-19 Pandemic on Laboratory and Clinical Research: A Testimony and a Call to Action From Researchers
HemaSphere · 2020 ·
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PubMed
Skrzypczak J, Pelzer B, Süli O.
Youth activists for our health
Lancet · 2019 ·
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PubMed
Zelin NS, Solotke MT, Scott CE, Atienza-Carbonell B, Fogas C, Skrzypczak J, Starin R, Tamburelli F, Ucar A, Pelzer B.
An Analysis of the Presence and Composition of OutLists at United States, Canadian, and European Medical Institutions
J Homosexuality · 2020 ·
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PubMed
Tölle D, Hentrich M, Pelzer B, Kremer P, Einhell S, Schulz S, Böll B, Panse J, Schmidt-Hieber M, Teschner D, Schalk E.
Impact of neutropenia on central venous catheter-related bloodstream infections in patients with hematological malignancies at the time of central venous catheter insertion: A matched-pair analysis
Infect Control Hosp Epidemiol · 2019 ·
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PubMed
Schuster M, Moeller M, Bornemann L, Bessen C, Sobczak C, Schmitz S, Witjes L, Kruithoff K, Kohn C, Just O, Kündgen A, Pundt N, Pelzer B, Ampe C, Van Troys M, Nusch A, Haas R, Germing U, Martens L, Jöckel KH, Gunzer M.
Surveillance of Myelodysplastic Syndrome via Migration Analyses of Blood Neutrophils: A Potential Prognostic Tool
J Immunol · 2018 ·
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PubMed
Pelzer B, Arendt M, Moebus S, Eisele L, Jöckel KH, Dührsen U, Dürig J; Heinz Nixdorf Recall Study Investigative Group
Light chain monoclonal gammopathy of undetermined significance is characterized by a high disappearance rate and low risk of progression on longitudinal analysis
Ann Hematol · 2018 ·
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PubMed
Pelzer B, Mickevičiūtė K.
Gender beliefs in medical students
Eur J Intern Med · 2017 ·
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PubMed
Pelzer B, Montvidas J, Rensen L.
Health-care access of transgender people: a medical student approach.
Lancet Diabetes Endocrinol · 2016 ·
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PubMed
Hardt SU, Papazoglou J, Pelzer B
Training: Common doctorates across Europe .
Nature · 2015 ·
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PubMed